Welcome to The Centre for Molecular Cell Biology
Our researchers study the biological organisation of cells, and the molecular mechanisms underpinning their function in health, disease and sustainable living. Our wide angle of exploration spans from the atomic structures and dynamics of living systems to their organisation in sub-cellular assemblies, cells, tissues, and organs. We are keen to translate of our fundamental discoveries into the drug discovery process, into clinical advances, and into the biotechnology industry. We commonly adopt an interdisciplinary approach including advanced imaging and genetic engineering techniques. This is frequently combined with high performance computing powered by artificial intelligence and machine learning. Collaboratively we address the grand challenges of food security, healthy ageing, anti-microbial resistance, green energy, and sustainable living.
News
24-02-2025
Faculty of Science and Engineering
06-12-2024
Faculty of Science and Engineering
Recent Publications
- The conserved Spd-2/CEP192 domain adopts a unique protein fold to promote centrosome scaffold assembly
Van Breugel M, HU L, WAINMAN A, ANDREEVA A, APIZI M, ALVAREZ-RODRIGO I, WONG S-S, SAURYA S, SHEPPARD D, COTTEE M, JOHNSON S, LEA SM, RAFF JW and FENG ZHE
Science Advances, American Association For The Advancement of Science
19-03-2025 - Author Correction: B-cell-specific checkpoint molecules that regulate anti-tumour immunity
Bod L, Kye Y-C, Shi J, Torlai Triglia E, Schnell A, Fessler J, Ostrowski SM, Von-Franque MY, Kuchroo JR, Barilla RM, Zaghouani S, Christian E, Delorey TM, Mohib K, Xiao S, Slingerland N, Giuliano CJ, Ashenberg O, Li Z, Rothstein DM, et al.
Nature, Springer Nature vol. 640 (8057), e1-e1.
17-03-2025 - Predicting the diversity of photosynthetic light-harvesting using thermodynamics and machine learning
Gray C, Chitnavis S, Buja T and Duffy CDP
Plos Computational Biology, Public Library of Science (Plos) vol. 21 (3)
11-03-2025
Recent Grants
- Career Development Award: Structural and mechanistic understanding of kinetochore-mediated control of microtubule dynamics
Vladimir Volkov
£2,044,077 Wellcome Trust
01-01-2025 - 31-12-2032 - i-GREENPHARM: AI and machine learning assisted development of greener formulations and pharmaceutical processes based on amorphous solid dispersions
Mohamed Elbadawi
£20,021
01-01-2025 - 31-12-2028 - Alteration in bacterial cell envelope structure as the mechanism of antibiotic resistance and cell death
Nikola Ojkic
£562,114 BBSRC Biotechnology and Biological Sciences Research Council
01-12-2024 - 30-11-2027